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Vampire Survivors – The Best Weapon Combinations to Use

Author : Zachary Update：Mar 16,2025

For fans of roguelike RPGs, Vampire Survivors needs no introduction. This bullet-hell styled game challenges you to control a character, dodging and attacking enemies without directly controlling attacks; your equipped weapons do the work. Unlike traditional RPGs, button-mashing is replaced by strategic movement. With multiple DLCs adding new weapons and combinations, mastering the best pairings is key. This guide highlights some of the deadliest and most efficient weapon combinations for maximum damage output. Let's dive in!

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Prism Lass + Glass Fandango

Prism Lass

  • Base Damage: 10
  • Max Level: 8
  • Evolves with Wings
  • Circles the character when evolved

Glass Fandango

  • Base Damage: 10
  • Max Level: 8
  • Increased damage against frozen enemies
  • Evolves with Wings

Vampire Survivors Guide Weapon Combination Guide EN2

The Prism Lass and Glass Fandango combination shares a unique trait: they prioritize attacking the nearest enemies in a targeted manner. Unlike area-of-effect (AOE) weapons, they deliver higher damage per hit but to fewer enemies simultaneously. The mid-game, particularly after the 20-minute mark, becomes significantly easier with this strategy. We recommend adding the King Bible as a fourth weapon; its protective barrier is invaluable when engaging enemies at close range.

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