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Path of Exile 2: The Slithering Dead Quest Guide

Author : Christian Update:Feb 25,2025

Path of Exile 2: The Slithering Dead Quest – A Comprehensive Guide

This guide covers the "Slithering Dead" side quest in Path of Exile 2, detailing its walkthrough and providing crucial advice on selecting the optimal quest rewards. The quest, initiated by Servi in the Ziggurat Encampment, involves uncovering the secrets of a rival tribe and the fate of her son, Apus.

The Slithering Dead Quest Walkthrough

  1. Locate the Venom Crypts: Access the Jungle Ruins map in Act 3 (and Act 3 Cruel). The Venom Crypts entrance is adjacent to the Jungle Ruins Waypoint. Note that while not crucial to the main storyline, it can be completed later in the game.

  1. Find the Corpse-Snake Venom: Explore the Venom Crypts until you discover a corpse within the Den of the Serpent Priestess. The corpse's location varies due to the randomized nature of PoE 2 maps.

  1. Return to Servi: Interact with the corpse to obtain the Corpse-Snake Venom. Return to the Ziggurat Encampment and give the venom to Servi to complete the quest.

Choosing the Best Venom Draught Rewards

The Slithering Dead is a repeatable quest, appearing in both Act 3 and Act 3 Cruel (Act 6). The rewards differ between acts, making each choice significant. Remember, your selection is permanent and irreversible.

Act 3 Reward Choices:

  • Venom Draught of Clarity (25% increased Mana Regeneration Rate): This is generally the best option, particularly beneficial for mana-hungry melee builds.

  • Venom Draught of the Veil (30% increased Elemental Ailment Threshold): A strong alternative, especially for builds less concerned with mana management and more vulnerable to elemental ailments.

  • Venom Draught of Stone (25% increased Stun Threshold): The least desirable option, unless your build heavily suffers from stun effects.

Act 3 Cruel (Act 6) Reward Choices:

  • Venom Draught of the Lost (+10% to Chaos Resistance): This is the superior choice in almost all cases, as Chaos Resistance is significantly harder to obtain through gear.

  • Venom Draught of the Sky (+5 to All Attributes): Only preferable for builds utilizing Chaos Inoculation (CI) with Eternal Youth.

  • Venom Draught of the Marshes (15% Reduced Slowing Potency of Debuffs on you): Generally less impactful than the other two options.

Careful consideration of your build's strengths and weaknesses is crucial for maximizing the benefits of your chosen Venom Draught. Choose wisely!

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